Titre :
  • Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated beta-cell death.
Auteur : Arif, Sefina ; Moore, Fabrice ; Marks, Katherine ; Bouckenooghe, Thomas ; Dayan, Colin M ; Planas, Raquel ; Vives-Pi, Marta ; Powrie, Jake ; Tree, Timothy ; Marchetti, Piero ; Huang, Guo Cai ; Gurzov, Esteban Nicolas ; Pujol-Borrell, Ricardo ; Eizirik, Decio L. ; Peakman, Mark
Informations sur la publication : Diabetes, 60, 8, (page 2112-2119)
Statut de publication : Publié, 2011
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Adolescent
Adult
Animals
Apoptosis -- drug effects
CD4-Positive T-Lymphocytes -- immunology
Cell Line, Tumor
Cytokines -- physiology
Diabetes Mellitus, Type 1 -- immunology
Female
Humans
Insulin-Secreting Cells -- drug effects -- pathology
Insulinoma -- metabolism
Interleukin-17 -- biosynthesis -- physiology
Interleukins -- biosynthesis
Male
NF-kappa B -- physiology
Nuclear Receptor Subfamily 1, Group F, Member 3 -- biosynthesis
Pancreatic Neoplasms -- metabolism
Rats
Rats, Wistar
STAT1 Transcription Factor -- physiology
Tumor Necrosis Factor-alpha -- physiology
Note : Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0012-1797 
info:doi/10.2337/db10-1643
info:pii/db10-1643
info:pmid/21659501
info:pmcid/PMC3142078