Titre:
  • Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated beta-cell death.
Auteur:Arif, Sefina; Moore, Fabrice; Marks, Katherine; Bouckenooghe, Thomas; Dayan, Colin M; Planas, Raquel; Vives-Pi, Marta; Powrie, Jake; Tree, Timothy; Marchetti, Piero; Huang, Guo Cai; Gurzov, Esteban Nicolas; Pujol-Borrell, Ricardo; Eizirik, Decio L.; Peakman, Mark
Informations sur la publication:Diabetes, 60, 8, page (2112-2119)
Statut de publication:Publié, 2011
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Adolescent
Adult
Animals
Apoptosis -- drug effects
CD4-Positive T-Lymphocytes -- immunology
Cell Line, Tumor
Cytokines -- physiology
Diabetes Mellitus, Type 1 -- immunology
Female
Humans
Insulin-Secreting Cells -- drug effects -- pathology
Insulinoma -- metabolism
Interleukin-17 -- biosynthesis -- physiology
Interleukins -- biosynthesis
Male
NF-kappa B -- physiology
Nuclear Receptor Subfamily 1, Group F, Member 3 -- biosynthesis
Pancreatic Neoplasms -- metabolism
Rats
Rats, Wistar
STAT1 Transcription Factor -- physiology
Tumor Necrosis Factor-alpha -- physiology
Note générale:Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0012-1797
info:doi/10.2337/db10-1643
info:pii/db10-1643
info:scp/80052829943
info:pmid/21659501
PMC3142078