Titre :
  • Phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway inhibition: a breakthrough in the management of luminal (ER+/HER2-) breast cancers?
Auteur : Zardavas, Dimitros ; Fumagalli, Debora ; Loi, Sherene
Informations sur la publication : Current opinion in oncology, 24, 6, (page 623-634)
Statut de publication : Publié, 2012-11
Sujet CREF : Sciences biomédicales
Cancérologie
Mots-clés MeSH : Antineoplastic Agents -- pharmacology -- therapeutic use
Breast Neoplasms -- drug therapy -- genetics -- metabolism
Clinical Trials as Topic
Drug Resistance, Neoplasm
Female
Humans
Phosphatidylinositol 3-Kinases -- antagonists & inhibitors -- genetics -- metabolism
Protein Kinase Inhibitors -- pharmacology -- therapeutic use
Receptor, erbB-2 -- metabolism
Receptors, Estrogen -- metabolism
Signal Transduction -- drug effects
Sirolimus -- pharmacology -- therapeutic use
TOR Serine-Threonine Kinases -- antagonists & inhibitors -- metabolism
Note : Journal Article
Research Support, Non-U.S. Gov't
Review
SCOPUS: re.j
Langue :
  • Anglais
Identificateurs : urn:issn:1040-8746 
info:doi/10.1097/CCO.0b013e328358a2b5
info:pmid/22960556