Titre :
  • PIK3CA genotype and a PIK3CA mutation-related gene signature and response to everolimus and letrozole in estrogen receptor positive breast cancer.
Auteur : Loi, Sherene ; Michiels, Stefan ; Baselga, José ; Bartlett, John M S ; Singhal, Sandeep K ; Sabine, Vicky S ; Sims, Andrew H ; Sahmoud, Tarek ; Dixon, J Michael ; Piccart-Gebhart, Martine ; Sotiriou, Christos
Informations sur la publication : PloS one, 8, 1, (page e53292)
Statut de publication : Publié, 2013
Sujet CREF : Cancérologie
Sciences biomédicales
Mots-clés MeSH : Aged
Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
Breast Neoplasms -- genetics -- metabolism
Cell Proliferation
Female
Gene Expression Regulation, Neoplastic
Genotype
Humans
Middle Aged
Mutation
Nitriles -- administration & dosage
Phosphatidylinositol 3-Kinases -- genetics
Receptors, Estrogen -- metabolism
Sirolimus -- administration & dosage -- analogs & derivatives
TOR Serine-Threonine Kinases -- metabolism
Triazoles -- administration & dosage
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:1932-6203 
info:doi/10.1371/journal.pone.0053292
info:pii/PONE-D-12-14015
info:pmid/23301057
info:pmcid/PMC3534682