Titre :
  • GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim
Auteur : Nogueira, Tatiane C ; Paula, Flavia M. ; Villate, Olatz ; Colli, Maikel L ; Moura, Rodrigo F ; Andrade Da Cunha, Daniel ; Marselli, Lorella ; Marchetti, Piero ; Cnop, Miriam ; Julier, Cécile ; Eizirik, Decio L.
Informations sur la publication : PLOS genetics, 9, 5, e1003532
Statut de publication : Publié, 2013
Sujet CREF : Médecine clinique [biologie clinique]
Mots-clés MeSH : Aged
Alternative Splicing -- genetics
Animals
Apoptosis -- genetics
Apoptosis Regulatory Proteins -- genetics -- metabolism
Diabetes Mellitus, Type 1 -- etiology -- genetics
Diabetes Mellitus, Type 2 -- etiology -- genetics
Female
Gene Knockdown Techniques
Humans
Insulin -- genetics
Insulin-Secreting Cells -- metabolism -- pathology
Male
Membrane Proteins -- genetics -- metabolism
Mice
Middle Aged
Protein Isoforms -- genetics
Proto-Oncogene Proteins -- genetics -- metabolism
Rats
Transcription Factors -- genetics
Note : SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:1553-7390 
info:doi/10.1371/journal.pgen.1003532
info:pii/PGENETICS-D-12-02709
info:pmid/23737756