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Influence of environmental iodine deficiency on neonatal thyroid screening results

par Carta Sorcini, M.;Diodato, A.;Fazzini, C.;Sabini, G.;Carta, S.;Grandolfo, M.;Guidi, Marco;Vasta, M.;Locatelli de Maestri, J.;Donati, L.;Romagnoli, C.;Luciano, R.;Bourdoux, Pierre ;Delange, François
Référence European journal of endocrinology, 11, page (309-312)
Publication Publié, 1988

Article révisé par les pairs

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Résumé :

During a multicentric pilot screening program for congenital hypothyroidism a comparison between the results obtained from Urbino, an area characterized by low iodine supply and endemic goiter, and Rome, a non-endemic area, has been made. The evaluation of neonatal urinary iodine excretion in the two areas showed significantly lower iodine urinary excretion levels in Urbino than in Rome. A shift of TSH at screening toward higher values as well as a higher percentage of recall in Urbino area than in Rome was observed. This finding, which well correlates with a low environmental iodine supply, emphasizes the importance of screening for congenital hypothyroidism as a suitable index of the presence and action of goitrogenic factors in the environment. © 1988, Italian Society of Endocrinology (SIE). All rights reserved.