Titre :
  • A conventional protein kinase C inhibitor targeting IRF-3-dependent genes differentially regulates IL-12 family members.
Auteur : Johnson, Jolyn ; Molle, Céline ; Aksoy, Ezra ; Goldman, Michel ; Goriely, Stanislas ; Willems, Fabienne
Informations sur la publication : Molecular immunology, 48, 12-13, (page 1484-1493)
Statut de publication : Publié, 2011-07
Sujet CREF : Immunologie
Mots-clés : IL-12
IL-23
IL-27p28
IRF-3
Protein kinase C
Toll-like receptor
Mots-clés MeSH : Animals
Carbazoles -- pharmacology
Dendritic Cells -- drug effects -- immunology -- metabolism
Gene Expression Regulation
Interferon Regulatory Factor-3 -- metabolism
Interleukin-12 -- biosynthesis -- genetics -- metabolism
Interleukin-17 -- biosynthesis -- genetics
Interleukin-23 -- biosynthesis -- genetics
Interleukins -- genetics -- metabolism
Lipopolysaccharides -- immunology
Mice
Mice, Transgenic
Poly I-C -- immunology
Polymerase Chain Reaction
Protein Kinase C -- antagonists & inhibitors -- metabolism
Toll-Like Receptor 3 -- metabolism
Toll-Like Receptor 4 -- metabolism
Transcription, Genetic -- drug effects
Note : Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0161-5890 
info:doi/10.1016/j.molimm.2011.04.006
info:pii/S0161-5890(11)00130-1
info:pmid/21550664