Articles dans des revues avec comité de lecture (93)
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Hana L, H., Chua, A., Pramila, G., Lakshminarayana, S. S., Singhal, A., Mathema, B., Wintjens, R., & Bifani, P. (2015). Mutations in the F420 biosynthetic pathway and a nitroreductase enzyme are the primary resistance determinants in spontaneous in vitro selected PA-824 mutants of Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy. doi:10.1128/AAC.00308-1530.
Dupré, E., Herrou, J., Lensink, M., Wintjens, R., Vagin, A., Lebedev, A., Crosson, S., Villeret, V., Locht, C., Antoine, R., & Jacob-Dubuisson, F. (2015). Virulence Regulation with Venus Flytrap Domains: Structure and Function of the Periplasmic Moiety of the Sensor-Kinase BvgS. P L o S Pathogens, 11(3), e1004700. doi:10.1371/journal.ppat.100470031.
Villemagne, B., Flipo, M., Blondiaux, N., Crauste, C., Malaquin, S., Leroux, F., Piveteau, C., Villeret, V., Brodin, P., Villoutreix, B. O., Sperandio, O., Soror, S. H., Wohlkonig, A., Wintjens, R., Déprez, B., Baulard, A., & Willand, N. (2014). Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking Approaches. Journal of medicinal chemistry, 57(11), 4876-4888. doi:10.1021/jm500422b33.
Berger, G., Soubhye, J., Van Der Lee, A., Vande Velde, C., Wintjens, R., Dubois, P., Clement, S., & Meyer, F. (2014). Interplay between halogen bonding and lone pair-Pi interactions: A computational and crystal packing study. ChemPlusChem, 79(4), 552-558. doi:10.1002/cplu.20140000534.
Huet, J., Mbosso, E. J. T., Soror, S. H., Meyer, F., Looze, Y., Wintjens, R., & Wohlkonig, A. (2013). High-resolution structure of a papaya plant-defence barwin-like protein solved by in-house sulfur-SAD phasing. Acta crystallographica. Section D, Biological crystallography, 69(10), 2017. doi:10.1107/S090744491301801535.
Pethe, K., Bifani, P., Jang, J., Kang, S., Park, S., Ahn, S., Jiricek, J., Jung, J., Jeon, H. K., Cechetto, J., Christophe, T., Lee, H., Kempf, M., Jackson, M., Lenaerts, A. J., Pham, H. O., Jones, V., Seo, M. J., Kim, Y. M., Seo, M., Seo, J. J., Park, D., Ko, Y., Choi, I., Kim, R., Kim, S. Y., Lim, S., Yim, S.-A., Nam, J., Kang, H., Kwon, H., Oh, C.-T., Cho, Y., Jang, Y., Kim, J., Chua, A., Tan, B. H., Nanjundappa, M. B., Rao, S. P. S., Barnes, W. S., Wintjens, R., Walker, J. R., Alonso, S., Lee, S., Kim, J., Oh, S., Oh, T., Nehrbass, U., Han, S.-J., No, Z., Lee, J., Brodin, P., Cho, S.-N., Nam, K., & Kim, J. (2013). Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. Nature medicine, 19(9), 1157-1160. doi:10.1038/nm.326236.
Mbosso, E. J. T., Wintjens, R., Lenta, B. N., Ngouela, S., Rohmer, M., & Tsamo, E. (2013). Chemical constituents from Glyphaea brevis and Monodora myristica: chemotaxonomic significance. Chemistry & biodiversity, 10(2), 224-232. doi:10.1002/cbdv.20110037837.
Deschuyteneer, A., Boeckstaens, M., De Mees, C., Van Vooren, P., Wintjens, R., & Marini, A. M. (2013). SNPs Altering Ammonium Transport Activity of Human Rhesus Factors Characterized by a Yeast-Based Functional Assay. PloS one, 8(8), e71092. doi:10.1371/journal.pone.007109238.
Stoffels, K., Mathys, V., Fauville, M., Wintjens, R., & Bifani, P. (2012). Systematic analysis of pyrazinamide-resistant spontaneous mutants and clinical isolates of Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 56(10), 5186-5193. doi:10.1128/AAC.05385-1139.
Mbosso, E. J. T., Nguedia, J. C. A., Meyer, F., Lenta, B. N., Ngouela, S., Lallemand, B., Mathieu, V., Van Antwerpen, P., Njunda, A. L., Adiogo, D. D., Tsamo, E., Looze, Y., Kiss, R., & Wintjens, R. (2012). Ceramide, cerebroside and triterpenoid saponin from the bark of aerial roots of Ficus elastica (Moraceae). Phytochemistry, 83, 95-103. doi:10.1016/j.phytochem.2012.07.01040.
Flipo, M., Willand, N., Lecat-Guillet, N., Hounsou, C., Desroses, M., Leroux, F., Lens, Z., Villeret, V., Wohlkonig, A., Wintjens, R., Christophe, T., Kyoung Jeon, H., Locht, C., Brodin, P., Baulard, A., & Déprez, B. (2012). Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis. Journal of medicinal chemistry, 55(14), 6391-6402. doi:10.1021/jm300377g