Articles dans des revues avec comité de lecture (93)
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Flipo, M., Frita, R., Bourotte, M., Martínez-Martínez, M. S., Boesche, M., Boyle, G. W., Derimanov, G., Drewes, G., Gamallo, P., Ghidelli-Disse, S., Gresham, S., Jiménez, E., de Mercado, J., Pérez-Herrán, E., Porras-De Francisco, E., Rullas, J., Casado, P., Leroux, F., Piveteau, C., Kiass, M., Mathys, V., Soetaert, K., Megalizzi, V., Tanina, A., Wintjens, R., Antoine, R., Brodin, P., Delorme, V., Moune, M., Djaout, K., Slupek, S., Kemmer, C., Gitzinger, M., Ballell, L., Mendoza-Losana, A., Lociuro, S., Déprez, B., Barros-Aguirre, D., Remuiñán, M. M., Willand, N., & Baulard, A. R. (2022). The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis. Science Translational Medicine, 14(643), eaaz6280. doi:10.1126/scitranslmed.aaz62806.
Demaret, T., Wintjens, R., Sana, G., Docquir, J., Bertin, F., Ide, C., Monestier, O., Karadurmus, D., Benoit, V., & Maystadt, I. (2022). Case Report: Inactivating PTH/PTHrP Signaling Disorder Type 1 Presenting With PTH Resistance. Frontiers in endocrinology, 13, 928284. doi:10.3389/fendo.2022.9282847.
Battisti, G., Wintjens, R., Decottignies, A., Merhi, A., Fervaille, C., Sokal, E. M., Karadurmus, D., Benoit, V., Claessens, A., Martinet, J.-P., Martiat, B., Kinzinger, P., & Maystadt, I. (2021). Child to adulthood clinical description of MDPL syndrome due to a novel variant in POLD1. European journal of medical genetics, 64(12), 104333. doi:10.1016/j.ejmg.2021.1043339.
Mbosso Teinkela, J. E., Siwe Noundou, X., Zeh Mimba, J. E., Meyer, F., Tabouguia, O. M., Assob Nguedia, J. C., Hoppe, H. H., Krause, R. W. M., Wintjens, R., & Azebaze, G. A. B. (2020). Compound isolation and biological activities of Piptadeniastrum africanum (hook.f.) Brennan roots. Journal of ethnopharmacology, 255, 112716. doi:10.1016/j.jep.2020.11271610.
Faïon, L., Djaout, K., Frita, R., Pintiala, C., Cantrelle, F.-X., Moune, M., Vandeputte, A., Bourbiaux, K., Piveteau, C., Herledan, A., Biela, A., Leroux, F., Kremer, L., Blaise, M., Tanina, A., Wintjens, R., Hanoulle, X., Déprez, B., Willand, N., Baulard, A. R., & Flipo, M. (2020). Discovery of the first Mycobacterium tuberculosis MabA (FabG1) inhibitors through a fragment-based screening. European journal of medicinal chemistry, 200, 112440. doi:10.1016/j.ejmech.2020.11244011.
Villemagne, B., Machelart, A., Tran, N. C., Flipo, M., Moune, M., Leroux, F., Piveteau, C., Wohlkönig, A., Wintjens, R., Li, X., Gref, R., Brodin, P., Déprez, B., Baulard, A. R., & Willand, N. (2020). Fragment-Based Optimized EthR Inhibitors with in Vivo Ethionamide Boosting Activity. ACS infectious diseases, 6(3), 366-378. doi:10.1021/acsinfecdis.9b0027712.
Brito, A. S., Neuhäuser, B., Wintjens, R., Marini, A. M., & Boeckstaens, M. (2020). Yeast filamentation signaling is connected to a specific substrate translocation mechanism of the Mep2 transceptor. PLOS genetics, 16(2), e1008634. doi:10.1371/journal.pgen.100863413.
Fouokeng, Y., Feumo Feusso, H., Mbosso Teinkela, J. E., Siwe Noundou, X., Wintjens, R., Isaacs, M., Hoppe, H. H., Krause, R. W. M., Azebaze, A. G. B., & Vardamides, J. C. (2019). In vitro antimalarial, antitrypanosomal and HIV-1 integrase inhibitory activities of two Cameroonian medicinal plants: Antrocaryon klaineanum (Anacardiaceae)and Diospyros conocarpa (Ebenaceae). South African journal of botany, 122, 510-517. doi:10.1016/j.sajb.2018.10.00814.
Prevet, H., Moune, M., Tanina, A., Kemmer, C., Herledan, A., Frita, R., Wohlkonig, A., Bourotte, M., Villemagne, B., Leroux, F., Gitzinger, M., Baulard, A., Déprez, B., Wintjens, R., Willand, N., & Flipo, M. (2019). A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2. European journal of medicinal chemistry, 167, 426-438. doi:10.1016/j.ejmech.2019.02.02315.
Tanina, A., Wohlkonig, A., Soror, S. H., Flipo, M., Villemagne, B., Prevet, H., Déprez, B., Moune, M., Perée, H., Meyer, F., Baulard, A., Willand, N., & Wintjens, R. (2019). A comprehensive analysis of the protein-ligand interactions in crystal structures of Mycobacterium tuberculosis EthR. Biochimica et biophysica acta. Proteins and proteomics, 1867(3), 248-258. doi:10.1016/j.bbapap.2018.12.00316.
Berger, G., Soubhye, J., Wintjens, R., Robeyns, K., & Meyer, F. (2018). Crystal packing and theoretical analysis of halogen- and hydrogen-bonded hydrazones from pharmaceuticals. Evidence of type I and II halogen bonds in extended chains of dichloromethane. Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials, 74(6), 618-627. doi:10.1107/S2052520618014221