par Huez, Sandrine 
;Vachiery, Jean-Luc ;Naeije, Robert
Référence Cardiovascular ultrasound, 7, page (9)
Publication Publié, 2009
;Vachiery, Jean-Luc ;Naeije, Robert Référence Cardiovascular ultrasound, 7, page (9)
Publication Publié, 2009
Article révisé par les pairs
| Résumé : | A right heart catheterization with reversibility testing is recommended for the diagnosis and treatment of pulmonary arterial hypertension. In this 24 years-old woman, the inhalation of 5 microg iloprost transiently decreased mean pulmonary artery pressure from 62 to 36 mmHg and pulmonary vascular resistance from 11.0 to 4.9 Wood units, meeting the criteria of a "positive response". The echocardiographic examination showed normalization of right heart chamber dimensions and of the right ventricular performance (Tei) index. Pulsed tissue Doppler imaging of the right ventricle showed a decrease in the isovolumic relaxation time from 102 to 73 ms, and an increase of the E/A ratio from 0.72 to 1.38, together with marked improvements in mid-apical free wall systolic strain and strain rate. A positive response to reversibility testing of pulmonary arterial hypertension may be associated with quasi normalization of right ventricular function, in spite of still elevated pulmonary artery pressure. |
