Article révisé par les pairs
Titre :
  • Identifying mechanisms of chronotolerance and chronoefficacy for the anticancer drugs 5-fluorouracil and oxaliplatin by computational modeling.
Auteur : Altinok, Atilla ; Lévi, Francis ; Goldbeter, Albert
Informations sur la publication : European journal of pharmaceutical sciences, 36, 1, (page 20-38)
Statut de publication : Publié, 2009-01
Sujet CREF : Chimie
Mots-clés : Cancer Chronotherapy
Cell Cycle
Chronotolerance
Circadian Rhythms
Glutathione
Model
Mots-clés MeSH : Algorithms
Animals
Antimetabolites, Antineoplastic -- pharmacokinetics
Antimetabolites, Antineoplastic -- therapeutic use
Antineoplastic Agents -- pharmacokinetics
Antineoplastic Agents -- therapeutic use
Cell Cycle -- drug effects
Circadian Rhythm -- physiology
Fluorouracil -- pharmacokinetics
Fluorouracil -- therapeutic use
Glutathione -- metabolism
Humans
Models, Statistical
Organoplatinum Compounds -- pharmacokinetics
Organoplatinum Compounds -- therapeutic use
Note : Journal Article
Research Support, Non-U.S. Gov't
Review
Langue :
  • Anglais
Identificateurs : urn:issn:0928-0987 
info:doi/10.1016/j.ejps.2008.10.024
info:pii/S0928-0987(08)00441-7
info:pmid/19041394