par Larsimont, Denis 
;Kiss, Robert ;D'Olne, Dominique ;De Launoit, Yvan ;Mattheiem, Wolrad ;Paridaens, R. ;Pasteels, Jean Lambert ;Verhest, Alain
Référence Analytical and quantitative cytology and histology, 11, 6, page (433-439)
Publication Publié, 1989-12
;Kiss, Robert ;D'Olne, Dominique ;De Launoit, Yvan ;Mattheiem, Wolrad ;Paridaens, R. ;Pasteels, Jean Lambert ;Verhest, AlainRéférence Analytical and quantitative cytology and histology, 11, 6, page (433-439)
Publication Publié, 1989-12
Article révisé par les pairs
| Résumé : | A pilot study analyzed the relationship between several morphonuclear parameters and the Bloom-Richardson score for 37 invasive, not-otherwise-specified (NOS) ductal breast carcinomas. The SAM-BA 200 cell image processor and its software were used to measure the nuclear features on Feulgen-stained imprint smears. Two parameters representing the numbers of large and dense chromatin clots and two parameters describing the heterogeneity of the chromatin among nuclei in a specimen evolved in a continuous manner parallel with the Bloom-Richardson score from stages NOS-4 to NOS-8. The systematic measurement of these four parameters on a large series of breast cancers may be able to define an objective and reproducible "scale" of differentiation that could be a helpful tool for pathologists and clinicians. |
