Titre :
  • Aristolochic acid induces proximal tubule apoptosis and epithelial to mesenchymal transformation.
Auteur : Pozdzik, Agnieszka ; Salmon, Isabelle ; Debelle, Frédéric ; Decaestecker, Christine ; Van den Branden, C ; Verbeelen, Dirk ; Deschodt Lanckman, Monique ; Vanherweghem, Jean-Louis ; Nortier, Joëlle
Informations sur la publication : Kidney international, 73, 5, (page 595-607)
Statut de publication : Publié, 2008-03
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Apoptosis
Aristolochic acid nephropathy
Myofibroblast
Oxidative stress
Proximal tubular cell
Transforming growth factor-β
Mots-clés MeSH : Animals
Apoptosis
Aristolochic Acids -- toxicity
Cell Proliferation
Chemokine CCL2 -- urine
Collagen -- analysis
Collagen -- metabolism
DNA Damage
DNA Repair
Epithelium -- drug effects
Epithelium -- pathology
Fibrosis
Ki-67 Antigen -- analysis
Kidney Diseases -- chemically induced
Kidney Diseases -- pathology
Kidney Tubules, Proximal -- chemistry
Kidney Tubules, Proximal -- drug effects
Kidney Tubules, Proximal -- pathology
Male
Mesoderm -- pathology
Mitochondria -- pathology
Mutagens -- toxicity
Oxidative Stress
Rats
Rats, Wistar
Receptor Protein-Tyrosine Kinases -- analysis
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0085-2538 
info:doi/10.1038/sj.ki.5002714
info:pii/5002714
info:pmid/18094681