par Burny, Wivine ;Liesnard, Corinne ;donner, catherine ;Marchant, Arnaud
Référence Expert review of anti-infective therapy, 2, 6, page (881-894)
Publication Publié, 2004-12
Article révisé par les pairs
Résumé : Cytomegalovirus is the most common cause of congenital infection. Congenital cytomegalovirus infection can follow both primary and recurrent maternal infections. It is associated with a significant burden of disease and death. The determinants of mother-to-child transmission and the pathogenesis of symptomatic fetal infection remain poorly understood. For a long time, congenital cytomegalovirus infection has been a neglected disease. Recently, the Institute of Medicine has recognized that the development of a vaccine against congenital cytomegalovirus infection is a public health priority, which should stimulate research in this area. The development of antiviral therapies to prevent symptoms in infected newborns also represents an important area of research.