Titre :
  • Regulation and function of the cytosolic viral RNA sensor RIG-I in pancreatic beta cells.
Auteur : García, Mónica ; Dogusan, Zeynep ; Moore, Fabrice ; Sato, Shintaro ; Hartmann, Gunther ; Eizirik, Decio L. ; Rasschaert, Joanne
Informations sur la publication : Biochimica et biophysica acta, 1793, 11, (page 1768-1775)
Statut de publication : Publié, 2009
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Apoptosis
Diabetes
RNA helicases
Toll-like receptor 3
Mots-clés MeSH : Animals
Apoptosis -- drug effects
Apoptosis -- genetics
Cytosol -- enzymology
Cytosol -- virology
DEAD-box RNA Helicases -- biosynthesis
Enterovirus -- metabolism
Enterovirus Infections -- enzymology
Enterovirus Infections -- genetics
Gene Deletion
Gene Expression Regulation, Enzymologic -- drug effects
Gene Expression Regulation, Enzymologic -- genetics
Insulin-Secreting Cells -- enzymology
Insulin-Secreting Cells -- virology
Interferon-beta -- biosynthesis
Male
Membrane Proteins -- biosynthesis
Mice
Mice, Knockout
NF-kappa B -- metabolism
Nerve Tissue Proteins -- biosynthesis
Poly I-C -- pharmacology
Promoter Regions, Genetic -- genetics
RNA, Double-Stranded -- metabolism
RNA, Viral -- metabolism
Rats
Rats, Wistar
Toll-Like Receptor 3 -- genetics
Toll-Like Receptor 3 -- metabolism
Up-Regulation -- drug effects
Up-Regulation -- genetics
Note : Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0006-3002 
info:doi/10.1016/j.bbamcr.2009.09.005
info:pii/S0167-4889(09)00230-4
info:pmid/19747951