Titre :
  • The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.
Auteur : Marchetti, Piero ; Bugliani, M. ; Lupi, R. ; Marselli, L ; Masini, Mathilde ; Boggi, U ; Filipponi, F ; Weir, G. ; Eizirik, Decio L. ; Cnop, Miriam
Informations sur la publication : Diabetologia, 50, 12, (page 2486-2494)
Statut de publication : Publié, 2007
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Beta cell
BiP
C/EBP homologous protein
CHOP
Endoplasmic reticulum
Immunoglobulin heavy chain binding protein
Unfolded protein response
X-box binding protein 1
XBP-1
Mots-clés MeSH : Aged
Apoptosis -- physiology
Cells, Cultured
DNA-Binding Proteins -- genetics
DNA-Binding Proteins -- metabolism
Diabetes Mellitus, Type 2 -- genetics
Diabetes Mellitus, Type 2 -- pathology
Diabetes Mellitus, Type 2 -- physiopathology
Endoplasmic Reticulum -- metabolism
Endoplasmic Reticulum -- pathology
Endoplasmic Reticulum -- physiology
Endoplasmic Reticulum -- ultrastructure
Female
Gene Expression -- drug effects
Gene Expression Profiling
Glucose -- pharmacology
Heat-Shock Proteins -- genetics
Heat-Shock Proteins -- metabolism
Humans
Insulin -- secretion
Insulin-Secreting Cells -- pathology
Insulin-Secreting Cells -- physiology
Insulin-Secreting Cells -- secretion
Insulin-Secreting Cells -- ultrastructure
Islets of Langerhans -- drug effects
Islets of Langerhans -- metabolism
Male
Middle Aged
Molecular Chaperones -- genetics
Molecular Chaperones -- metabolism
Nuclear Proteins -- genetics
Nuclear Proteins -- metabolism
Oligonucleotide Array Sequence Analysis
Transcription Factor CHOP -- genetics
Transcription Factor CHOP -- metabolism
Transcription Factors
Note : Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langue :
  • Anglais
Identificateurs : urn:issn:0012-186X 
info:doi/10.1007/s00125-007-0816-8
info:pmid/17906960