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Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist.

par Vlaeminck-Guillem, Virginie;Ho, Su Chin;Rodien, P;Vassart, Gilbert ;Costagliola, Sabine
Référence Molecular endocrinology, 16, 4, page (736-746)
Publication Publié, 2002-04

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Titre:	Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist.
Auteur:	Vlaeminck-Guillem, Virginie; Ho, Su Chin; Rodien, P; Vassart, Gilbert; Costagliola, Sabine
Informations sur la publication:	Molecular endocrinology, 16, 4, page (736-746)
Statut de publication:	Publié, 2002-04
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Amino Acid Sequence
	Animals
	COS Cells
	Cattle
	Cyclic AMP -- physiology
	Electrophoresis, Polyacrylamide Gel
	Humans
	Models, Chemical
	Molecular Sequence Data
	Mutagenesis, Site-Directed
	Protein Conformation
	Protein Sorting Signals
	Protein Structure, Secondary
	Receptors, Thyrotropin -- physiology
	Rhodopsin -- chemistry
	Structure-Activity Relationship
	Thyrotropin -- metabolism
Note générale:	Journal Article
Langue:	Anglais
Identificateurs:	urn:issn:0888-8809
	info:doi/10.1210/me.16.4.736
	info:scp/0036214718
	info:pmid/11923470