Titre :
  • Catalytic mechanism of Escherichia coli isopentenyl diphosphate isomerase involves Cys-67, Glu-116, and Tyr-104 as suggested by crystal structures of complexes with transition state analogues and irreversible inhibitors
Auteur : Wouters, Johan ; Oudjama, Yamina ; Barkley, Sam J. ; Tricot, Catherine ; Stalon, Victor ; Droogmans, Louis ; Poulter, C. Dale
Informations sur la publication : The Journal of biological chemistry, 278, 14, (page 11903-11908)
Statut de publication : Publié, 2003-04
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés MeSH : Carbon-Carbon Double Bond Isomerases -- antagonists & inhibitors
Carbon-Carbon Double Bond Isomerases -- chemistry
Carbon-Carbon Double Bond Isomerases -- metabolism
Catalytic Domain
Crystallography
Cysteine -- chemistry
Epoxy Compounds -- pharmacology
Escherichia coli -- enzymology
Glutamic Acid -- chemistry
Kinetics
Organophosphorus Compounds -- pharmacology
Protein Structure, Secondary
Tyrosine -- chemistry
Note : Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0021-9258 
info:doi/10.1074/jbc.M212823200
info:pii/M212823200
info:pmid/12540835
VX-005389