Titre :
  • Valproate synergizes with purine nucleoside analogues to induce apoptosis of B-chronic lymphocytic leukaemia cells.
Auteur : Bouzar, Amel Baya ; Boxus, Mathieu ; Defoiche, Julien ; Berchem, Guy ; Macallan, Derek ; Pettengell, Ruth ; Willis, Fenella ; Burny, A. ; Lagneaux, Laurence ; Bron, Dominique ; Chatelain, Bernard ; Chatelain, Christian ; Willems, Lucas
Informations sur la publication : British journal of haematology, 144, 1, (page 41-52)
Statut de publication : Publié, 2009-01
Sujet CREF : Sciences bio-médicales et agricoles
Mots-clés : Apoptosis
Chronic lymphocytic leukaemia
Cladribine
Fludarabine
Valproate
Mots-clés MeSH : Adult
Aged
Aged, 80 and over
Antineoplastic Agents -- therapeutic use
Apoptosis -- drug effects
Blotting, Western -- methods
Cladribine -- therapeutic use
Drug Synergism
Enzyme Inhibitors -- therapeutic use
Female
Histone Deacetylase Inhibitors
Humans
Leukemia, Lymphocytic, Chronic, B-Cell -- drug therapy
Leukemia, Lymphocytic, Chronic, B-Cell -- pathology
Male
Microscopy, Confocal
Middle Aged
Reactive Oxygen Species -- metabolism
Tumor Cells, Cultured
Valproic Acid -- therapeutic use
Vidarabine -- analogs & derivatives
Vidarabine -- therapeutic use
Note : Journal Article
Research Support, Non-U.S. Gov't
FLWIN
Langue :
  • Anglais
Identificateurs : urn:issn:0007-1048 
info:doi/10.1111/j.1365-2141.2008.07426.x
info:pii/BJH7426
info:pmid/19006566