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A Microdialysis probe coupled with a miniaturized thermal glucose sensor for in vivo monitoring

par Amine, Aziz ;Digua, Khalid ;Xie, Bin;Danielsson, Bengt
Référence Analytical letters, 28, 13, page (2275-2286)
Publication Publié, 1995

Article révisé par les pairs

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Résumé :

A miniaturized thermal flow injection analysis biosensor has been coupled with a microdialysis probe for continuous subcutaneous glucose monitoring. Thermal biosensors are based on the principle of measuring the heat evolved during enzyme catalysed reactions. The system presented here consists of a miniaturized thermal biosensor with a small column containing coimmibolized glucose oxidase and catalase. The analysis buffer passes through the column at a flow rate of 60uL/min via an 1uL sample loop which is connected to a microdialysis probe. © 1995, Taylor & Francis Group, LLC. All rights reserved.