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MALDI-TOF MS typing of a nosocomial methicillin-resistant Staphylococcus aureus outbreak in a neonatal intensive care unit.

par Steensels, Deborah ;Deplano, Ariane ;Denis, Olivier ;Simon, Anne;Verroken, Alexia
Référence Acta Clinica Belgica (English ed. Printed), page (1-7)
Publication Publié, 2016-06

Article révisé par les pairs

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Résumé :

The early detection of a methicillin-resistant Staphylococcus aureus (MRSA) outbreak is decisive to control its spread and rapidly initiate adequate infection control measures. Therefore, prompt determination of epidemiologic relatedness of clinical MRSA isolates is essential. Genetic typing methods have a high discriminatory power but their availability remains restricted. In this study, we aimed to challenge matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) as a typing tool of a nosocomial MRSA outbreak in a neonatal intensive care unit.