par Schoutens, ELISABETH;Moens, Jean-Pierre ;Yourassowsky, Eugène
Référence Annales de la Société belge de médecine tropicale, 58, 2, page (111-117)
Publication Publié, 1978
Article révisé par les pairs
Résumé : Sera from 9 subjects with suspicion of chronic brucellosis were submitted to 7 well-known laboratories for diagnosis. They were free to select the methods. With the agglutination technique of Wright positive results were found in each serum by at least 1 of the 7 laboratories, but titers were not significant in 4 patients. For the 5 other patients significant titers were found by 1 to 3 laboratories, but 3 laboratories had frankly negative results for all samples submitted. Other methods (complement fixation test, Coombs' test, passive haemagglutination, immunofluorescence) were used by a number of participants. They tended to confirm the results of the Wright reaction in 3 out of the 5 persons with high agglutination titers. One of the patients had also a significant titer of anti-Yersinia antibodies in 1 of the 2 laboratories which performed this test. This survey confirms the necessity to standardize serological tests for the diagnosis of human brucellosis. Each laboratory should have a national or international standard reference serum.