Résumé : We present results from the first holographic bubble chamber experiment. Using topological information on the events observed in the heavy liquid bubble chamber HOBC, we have determined a total charm pair produc-tion cross section of (24.6ts+12.0 -8.3) μb and (3.9+2 -1:5 9) /μb in 360GeV/c and 200 GeV/c proton-nucleon interactions respectively. For these estimates we assumed a linear dependence of the charm cross section on the atomic number A. © 1986 IOP Publishing Ltd.