par Heinrichs, Claudine 
Référence Revue médicale de Bruxelles, 19, 6, page (471-473)
Publication Publié, 1998
Référence Revue médicale de Bruxelles, 19, 6, page (471-473)
Publication Publié, 1998
Article révisé par les pairs
| Résumé : | Intrauterine growth retardation (IUGR), defined as birth weight and/or length less than 3th percentile (P) or less than - 2 standard deviations (SD), concerns about 3 % of newborns. About 85 % born IUGR show spontaneous postnatal catch-up to a height > P3 or > - 2 SD during the first two years of life. After the age of 4 year, the children without catch-up will remain short up to final height. Classical growth hormone (GH) deficiency usually does not seem responsible for the absence of catch-up in those children. A two-year GH therapy at supraphysiological doses increases growth velocity. The effect of this treatment on final height remains to be studied, as well as optimal treatment's modalities. Attention should be paid on the possible side-effects. Finally, the evaluation of the psychological impact of GH treatment will be critical. |
