par Biot, Christophe ;François, Nadine;Maciejewski, Lucien;Brocard, Jacques;Poulain, Daniel
Référence Bioorganic & medicinal chemistry, 10, 8, page (839-841)
Publication Publié, 2000
Référence Bioorganic & medicinal chemistry, 10, 8, page (839-841)
Publication Publié, 2000
Article révisé par les pairs
Résumé : | A novel ferrocene-fluconazole analogue was synthesized and its antifungal properties investigated against yeast strains of medical importance, including those intrinsically resistant to fluconazole. In vitro tests revealed a slight increase in fungal growth and a reversal of the effect of fluconazole at minimal inhibitory concentrations. (C) 2000 Elsevier Science Ltd. All rights reserved. |