par Mitoma, Hiroshi;Adhikari, Keya;Aeschlimann, Daniel;Chattopadhyay, Partha;Hadjivassiliou, Marios;Hampe, Christiane Susanne;Honnorat, Jerome;Joubert, Bastien;Kakei, Shinji;Lee, Jongho;Manto, Mario 
;Matsunaga, Akiko;Mizusawa, Hidehiro;Nanri, Kazunori;Shanmugarajah, Priya;Yoneda, Makoto;Yuki, Nobuhiro
Référence Cerebellum
Publication Publié, 2015-03
;Matsunaga, Akiko;Mizusawa, Hidehiro;Nanri, Kazunori;Shanmugarajah, Priya;Yoneda, Makoto;Yuki, NobuhiroRéférence Cerebellum
Publication Publié, 2015-03
Article révisé par les pairs
| Résumé : | In the last few years, a lot of publications suggested that disabling cerebellar ataxias may develop through immune-mediated mechanisms. In this consensus paper, we discuss the clinical features of the main described immune-mediated cerebellar ataxias and address their presumed pathogenesis. Immune-mediated cerebellar ataxias include cerebellar ataxia associated with anti-GAD antibodies, the cerebellar type of Hashimoto's encephalopathy, primary autoimmune cerebellar ataxia, gluten ataxia, Miller Fisher syndrome, ataxia associated with systemic lupus erythematosus, and paraneoplastic cerebellar degeneration. Humoral mechanisms, cell-mediated immunity, inflammation, and vascular injuries contribute to the cerebellar deficits in immune-mediated cerebellar ataxias. |
