par Gingras, Isabelle;Desmedt, Christine 
;Ignatiadis, Michail ;Sotiriou, Christos
Référence Clinical cancer research, 21, 21, page (4743-4746)
Publication Publié, 2015-11
;Ignatiadis, Michail ;Sotiriou, Christos Référence Clinical cancer research, 21, 21, page (4743-4746)
Publication Publié, 2015-11
Article révisé par les pairs
| Résumé : | Desmedt and colleagues published two articles, one in the June 1, 2007 issue, and the other in the August 15, 2008, issue of Clinical Cancer Research, that showed gene-expression signatures to be proliferation driven and time dependent, with their prognostic power decreasing with increasing follow-up years. Moreover, the articles showed that immune response is a crucial determinant of prognosis in the HER2-positive and estrogen receptor-negative/HER2-negative subtypes, providing a rationale to further explore the role of the antitumor immune response in these breast cancer subtypes. Clin Cancer Res; 21(21); 4743-6. ©2015 AACR.See related articles by Desmedt et al., Clin Cancer Res 2007;13(11) June 1, 2007;3207-14 and Desmedt et al., Clin Cancer Res 2008;14(16) August 15, 2008;5158-65. |
