par Alexandre, Henri 
Référence Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D, Sciences naturelles, 286, 16, page (1215-1217)
Publication Publié, 1978
Référence Comptes rendus hebdomadaires des séances de l'Académie des sciences. Série D, Sciences naturelles, 286, 16, page (1215-1217)
Publication Publié, 1978
Article révisé par les pairs
| Résumé : | Alpha-Methylornithine, an inhibitor of the synthesis of putrescine does not affect the cleavage of Mouse eggs, cultured in vitro from the 2-cell stage, before blastocyst formation, whereas methylglyoxal-Bis (guanylhydrazone), an inhibitor of the syntheses of spermidine and spermine induces the embryos to become quiescent at about the 8-cell stage; resumption of their development, after transfer to fresh medium, is followed by a delay in cavitation. These results may be related to the biological clock theory for primary differentiation. |
