Are anti-vitamin K drugs contraindicated with cetuximab during head-and-neck cancer concomitant radiotherapy?

Brohée, Dany; Henry, Anne Rose; Castadot, Pierre

doi:doi/10.2143/ACB.3305

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Are anti-vitamin K drugs contraindicated with cetuximab during head-and-neck cancer concomitant radiotherapy?

par Brohée, Dany

;Henry, Anne Rose ;Castadot, Pierre
Référence Acta Clinica Belgica (English ed. Printed), 68, 3, page (237-239)
Publication Publié, 2013-06

Article révisé par les pairs

Résumé :

Two cases of severe skin reactions to cetuximab and concomitant radiation therapy are reported in patients treated for locally advanced head-and-neck squamous cell carcinoma and concurrently treated with an antivitamin K drug for cardiovascular diseases. The role of vitamin K in the epidermal growth factor/epidermal growth factor receptor pathway is discussed. A plea for a specific registry is entered.

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