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In vitro and in vivo activity of enduracidin on staphylococcus aureus

par Yourassowsky, Eugène ;Monsieur, Rita
Référence Chemotherapy, 17, 3, page (182-187)
Publication Publié, 1972

Article révisé par les pairs

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Résumé :

All strains of Staph. aureus isolated from pathological products are sensitive to less than 1µg/ml of enduracidin. Strains with an heterogeneous resistance to methicillin are also sensitive to the antibiotic. Intramuscular injections of enduracidin in guinea-pigs provide the serum of the animals with a rapid and complete bactericidal action on Staph. aureus ATCC 9801. A study of the activity curves shows that the speed of action of enduracidin in serum depends on the antibiotic concentration. © 1972 S. Karger AG, Basel.