par Haot, Jules 
;Mathy, Jean Pierre;Engelholm, Louis ;Meersseman, F.
Référence Acta gastro-enterologica Belgica (Ed. multilingue), 39, 11-12, page (585-594)
Publication Publié, 1976
;Mathy, Jean Pierre;Engelholm, Louis ;Meersseman, F.Référence Acta gastro-enterologica Belgica (Ed. multilingue), 39, 11-12, page (585-594)
Publication Publié, 1976
Article révisé par les pairs
| Résumé : | The histopathologic spectrum of lesions intervening in chronic pancreatitis is illustrated by 2 anatomopathologic series: the 1st one grouping 35 randomly chosen necropsy cases; the 2nd being composed of 15 surgical specimens. The necropsy series demonstrated the high frequency of 'minor' lesions characterized by canalicular ectasias and pericanalicular or perilobular fibrosis. In the surgical material more severe forms of chronic pancreatitis were observed. Two types of parenchymal injuries could be discriminated, with a different histologic composition and topographic distribution. The first one, most often found in the pancreas head, consists of scar like fibrosis disturbing the lobular structure, frequently accompanied by pseudocysts and calcifications. The second kind is essentially detected in the caudal region; fine bundles of fibrous tissue dissect the pancreatic lobules and acini which progressively disappear, leaving oval scars in which canalicular and endocrine metaplasias often develop (islet cell hyperplasias). This latter type of injury is presumably consequent to obstruction of the cephalic part of the pancreatic duct. |
