Severe bilateral panuveitis during melanoma treatment by Dabrafenib and Trametinib

Draganova, Dafina; Kerger, Joseph; Caspers, Laure; Willermain, Francois

doi:doi/10.1186/s12348-015-0049-9

Recherche avancée | Historique de recherche Mon DI-fusion | À propos de DI-fusion | Contact |

Citer

Severe bilateral panuveitis during melanoma treatment by Dabrafenib and Trametinib

par Draganova, Dafina

;Kerger, Joseph

;Caspers, Laure

;Willermain, Francois

Référence Journal of ophthalmic inflammation and infection, 5, 17
Publication Publié, 2015-06

Article révisé par les pairs

Résumé :

We report a case of severe bilateral panuveitis during melanoma therapy with a combination of Dabrafenib, a B-raf (BRAF) inhibitor, and Trametinib, a mitogen/extracellular signal-regulated kinase (MEK) inhibitor. Both of these drugs are effectors in the mitogen-activated protein kinase (MAPK) pathway, which plays an important role in the physiopathology of melanoma. Dabrafenib and Trametinib have shown improved survival of patients with metastatic melanoma but they have also been associated with the development of uveitis.

Documents en relation

DI-fusion

Clinical Utility of 18F-FDG PET/CT in the Work-up of Children with Uveitis
par Bazewicz, Magdalena , Makhoul, Dorine , Goffin, Laurence , El Mouden, Jamella , Judice De Menezes Relvas, Lia , Caspers, Laure , Draganova, Dafina , Postelmans, Laurence , Garcia, Camilo , Willermain, Francois
Publication 2023-08-01
Trocar Site Recurrence after Laparoscopic Cholecystectomy for Unsuspected Isolated Gallbladder Metastasis of Melanoma: A Case Report and Review of the Literature.
par Sergeant, Céline , Kerger, Joseph , Drowart, Annie , Sales, François , Langouo Fontsa, Mireille
Publication 2023-12-01
Ocular sarcoidosis in adults and children: update on clinical manifestation and diagnosis
par Bazewicz, Magdalena , Heissigerova, Jarmila , Pavesio, Carlos , Willermain, Francois , Skrzypecki, Janusz
Publication 2023-12
Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga
par Moris, Victoria , Bruneau, Lucie , Berthe, Jérémy , Heuskin, Anne-Catherine , Penninckx, Sébastien , Ritter, Sylvia , Weber, Uli , Durante, Marco , Danchin, Etienne E.G.J. , Hespeels, Boris , Doninck, Karine Van
Publication 2024-12
CDK4 phosphorylation status and rational use for combining CDK4/6 and BRAF/MEK inhibition in advanced thyroid carcinomas.
par Pita, Jaime Miguel , Raspé, Eric , Coulonval, Katia , Decaussin-Petrucci, Myriam , Tarabichi, Maxime , Dom, Geneviève , Libert, Frédérick , Ruscas-Craciun, Ligia Ioana , Andry, Guy , Wicquart, Laurence , Leteurtre, Emmanuelle , Tresallet, Christophe , Marlow, Laura A , Copland, John A , Durante, Cosimo , Maenhaut, Carine , Cavaco, Branca Maria , Dumont, Jacques Emile , Costante, Giuseppe , Roger, Pierre P.
Publication 2023-10-26

Référencement	Visibilité	Pérennité	Facilité
Les publications encodées constituent la bibliographie académique de l'Université.	Les documents déposés sont indexés par les moteurs de recherche (Google Scholar,…).	Les documents déposés en open-access sont archivés au sein du réseau de préservation SAFE-PLN (www.safepln.org).	Les listes de publications sont compatibles avec le CV-ULB, le FNRS et accessibles sur le web.