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An evolutionary scheme for the histones as derived from a study of internal repetitions and homologies among the different classes

par Wuilmart, Christian ;Wyns, Lode
Référence Journal of theoretical biology, 65, 2, page (231-252)
Publication Publié, 1977-03

Article révisé par les pairs

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Résumé :

An extensive search, using a computer performed sliding match, has been made for the occurrence of internal regularities (linear and inverted duplications) and for homologies between the five major histone classes. The observed intersequence homologies and internal duplications have led us to the proposal of an evolutionary scheme involving H2A, H2B and H4 as deriving from a common ancestor. However, it is shown that analysis of sequence information only, cannot sustain a conclusion to a common origin of all the histones. © 1977.