par Yernault, Jean Claude ;De Jonghe, Michel ;De Coster, Armand ;Englert, Marc
Référence BULL.PHYSIO-PATH.RESP., 11, 2, page (231-244)
Publication Publié, 1975
Article révisé par les pairs
Résumé : The mechanical and the diffusing lung properties have been measured in 19 cases of diffuse fibrosing alveolitis of unknown etiology (proved by histology in 17 cases). The characteristic findings are: a striking reduction in lung diffusing capacity for CO in all the cases; a marked reduction of the static and dynamic compliance, in correlation with the reduction of vital capacity; an increase in total lung capacity in correlation with the decrease of the helium dilution method; an increase of the elastic recoil when it is considered at various percentages of the predicted lung volume, but in some cases a normal shape of the volume pressure curve if the measured lung volume is taken into account; a reduction of the maximum expiratory flows suggesting bronchiolar stenosis; alterations of lung diffusing capacity (DL) more marked than those of lung compliance suggesting that DL is a more sensitive test.