Article révisé par les pairs
Résumé : Enterobacter cloacae is a bacterial species with inducible resistance to third-generation cephalosporins and to cefotaxime in particular. This inducible resistance was studied by kinetic turbidometry. With cefotaxime, three of five strains showed regrowth of resistant bacteria. With mecillinam alone, a slow regrowth of E cloacae cultures was observed. The combination of 1 μg/ml mecillinam and 1 μg/ml cefotaxime prevented the appearance of cefotaxime-resistant E cloacae.