par Delhaye, Myriam 
;Adler, Michael ;Balasse, P.;Verhas, Michel
Référence Acta gastro-enterologica Belgica (Ed. multilingue), 44, 3-4, page (171-186)
Publication Publié, 1981
;Adler, Michael ;Balasse, P.;Verhas, Michel Référence Acta gastro-enterologica Belgica (Ed. multilingue), 44, 3-4, page (171-186)
Publication Publié, 1981
Article révisé par les pairs
| Résumé : | A retrospective study was made of 97 patients with cirrhosis of the liver: the scintigraphic criteria of selection are the heterogeneity of the hepatic uptake, the hyperactivity of the spleen and the uptake by the bones. These criteria may be present either all together or in various combinations. The splenic hyperactivity is observed, alone or associated with other criteria, in 42.3% of the cirrhotic patients. By increasing the minimum number of scintigraphic criteria required for the diagnosis of cirrhosis, the sensitivity of the hepato-splenic scintigraphy decreases markedly, with an important increase in the number of false-negative scans. In contrast the total number of false-positive results decreases: this corresponds generally with a normal histology or with steatosis. Finally, the specificity of the method increases slightly, but the predictive value and the diagnostic efficiency especially are only poorly modified. The hepatosplenic scintigraphy - an easy to perform, non-aggressive investigation - is useful for the detection of a non specific disease of the liver (as shown in the literature). Our study shows that this investigation has no significant value as concerns sensitivity, predictive value and diagnostic efficiency, if the aim of the search is to detect cirrhosis of the liver: in such cases laparoscopy with liver biopsy provides a correct diagnosis more easily. |
