par Dargent, Jean-Louis 
;Delville, Jean Pierre;Kornreich, Anne ;Pradier, Olivier ;Cochaux, Pascale ;Velu, Thierry ;Capel, Paul ;Feremans, Walter ;Neve, Pierre
Référence Annals of hematology, 74, 3, page (149-153)
Publication Publié, 1997
;Delville, Jean Pierre;Kornreich, Anne ;Pradier, Olivier ;Cochaux, Pascale ;Velu, Thierry ;Capel, Paul ;Feremans, Walter ;Neve, Pierre Référence Annals of hematology, 74, 3, page (149-153)
Publication Publié, 1997
Article révisé par les pairs
| Résumé : | A particular case of marginal zone B-cell lymphoma (MZBCL) presenting with leukemic lymphocytes is reported. In the present observation, the leukemic cells not only displayed a remarkable morphological fluctuation but also had an unusual phenotype, changing with time. These phenotypic features, which have been functionally investigated by in vitro assays, might simply reflect an activation state depending on the microenvironment. Because of its disconcerting similarities with hairy cell leukemia (HCL) and splenic lymphoma with villous lymphocytes (SLVL), this case relaunches the debate about whether close relationships might exist between the splenic marginal zone, SLVL and HCL. |
