par Depasse, Jacques
Référence Environmental research, 27, 2, page (384-388)
Publication Publié, 1982
Article révisé par les pairs
Résumé : Sialic acid removal from human erythrocytes does not influence their susceptibility to chrysotile. This is in contradiction with the view that hemolysis by chrysotile is related to the clustering of membrane sialoproteins by the mineral. Sialic acid removal from horse erythrocytes slightly decreases their sensitivity toward chrysotile. As horse, but not human, erythrocytes contain lipid-bound sialic acid, it supports the proposal that interactions between chrysotile and the lipidic part of the membrane are responsible for the hemolytic activity of that mineral.