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Outcome for donors and recipients in two egg-sharing policies

par Kolibianakis, Efstratios;Tournaye, Herman;Osmanagaoglu, Kaan;Camus, Marguerite ;Van Waesberghe, Linda;Van Steirteghem, André;Devroey, Paul
Référence Fertility and sterility, 79, 1, page (69-73)
Publication Publié, 2003-01

Article révisé par les pairs

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Résumé :

Objective: To assess the effect of two different donation policies on results of egg-sharing. Design: Retrospective analysis. Setting: Tertiary referral center. Patient(s): One hundred five donor-recipient pairs participating in an egg-sharing program between 1998 and 2001. Intervention(s): Egg-sharing was performed according to policy A (retrieval of at least 12 oocytes, with more oocytes allocated to the donor) or policy B (retrieval of at least 8 oocytes, with equal distribution of oocytes between donors and recipients). Main Outcome Measure(s): Delivery rate and cycle cancellation rate. Result(s): Policy B resulted in a decreased cycle cancellation rate in the recipient group compared with policy A (9.7% vs. 29.7%, respectively; P≤.01). No significant difference in delivery rate per fresh transfer was observed between policy A and policy B in donors (30.2% vs. 27.8%, respectively) or recipients (28.2% vs. 25.7%, respectively). Conclusion(s): Decreasing the number of oocytes required to perform egg sharing from 12 to 8 and dividing the oocytes equally between donors and recipients significantly reduces the cycle cancellation rate while it does not appear to affect adversely the probability of delivery. © 2003 by American Society for Reproductive Medicine.