par Renard, Marc 
;Jacobs, Paul ;Liebens, Isabelle
Référence The American heart journal, 109, 3 II, page (720-722)
Publication Publié, 1985
;Jacobs, Paul ;Liebens, Isabelle Référence The American heart journal, 109, 3 II, page (720-722)
Publication Publié, 1985
Article révisé par les pairs
| Résumé : | We studied the effects of molsidomine on hemodynamic properties and blood gas levels in eight patients with acute myocardial infarction and left heart failure. One hour after an 8 mg intravenous bolus injection, pulmonary wedge pressure and right atrial pressure decreased, respectively, from 30 ± 9 to 23 ± 12 mm Hg (p < 0.01) and from 10.4 ± 3.6 to 7.8 ± 4.0 mm Hg (p < 0.05) without significant changes in heart rate, cardiac index, or systemic blood pressure. There was a mild decrease in arterial oxygen tension (from 61 ± 15 to 56 ± 6 mm Hg), but it was not significant. The drug induced no adverse effects. Intravenous bolus injection of molsidomine rapidly relieves pulmonary congestion in patients with acute myocardial infarction. © 1985. |
