An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units.

Wong, Gloria; Brinkman, Alexander; Benefield, Russell J; Carlier, Mieke; De Waele, Jan; El Helali, Najoua; Frey, Otto; Harbarth, Stephan; Huttner, Angela; McWhinney, Brett; Misset, Benoit; Pea, Federico; Preisenberger, Judit; Roberts, Michael S; Robertson, Thomas A; Roehr, Anka; Sime, Fekade Bruck; Taccone, Fabio; Ungerer, Jacobus P J; Lipman, Jeffrey; Roberts, Jason A

doi:doi/10.1093/jac/dkt523

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Article révisé par les pairs

Résumé :

Emerging evidence supports the use of therapeutic drug monitoring (TDM) of β-lactams for intensive care unit (ICU) patients to optimize drug exposure, although limited detail is available on how sites run this service in practice. This multicentre survey study was performed to describe the various approaches used for β-lactam TDM in ICUs.

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