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Safe single-dose administration of propofol in patients with established brugada syndrome: a retrospective database analysis.

par Flamée, Panagiotis;de Asmundis, Carlo;Bhutia, Jigme T;Conte, Giulio;Beckers, Stefan;Umbrain, Vincent;Verborgh, Christian;Chierchia, Gian-Battista;Van Malderen, Sophie;Casado Arroyo, Ruben ;Sarkozy, Andrea;Brugada, Pedro;Poelaert, Jan
Référence Pacing and clinical electrophysiology, 36, 12, page (1516-1521)
Publication Publié, 2013-12

Article révisé par les pairs

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Résumé :

Propofol is an anesthetic drug with a very attractive pharmacokinetic profile, which makes it the induction agent of choice, especially in day-case surgery. Data on its potential proarrhythmic effects in patients with Brugada syndrome (BS) patients are still lacking. The aim of our study was to investigate whether a single dose of propofol triggered any adverse events in consecutive high-risk patients with BS.