par Lelubre, Christophe 
;Anselin, Sophie;Zouaoui Boudjeltia, Karim ;Biston, Patrick ;Piagnerelli, Michaël
Référence Advances in hematology, 2013, page (124021)
Publication Publié, 2013
;Anselin, Sophie;Zouaoui Boudjeltia, Karim ;Biston, Patrick ;Piagnerelli, Michaël Référence Advances in hematology, 2013, page (124021)
Publication Publié, 2013
Article révisé par les pairs
| Résumé : | Infection is often difficult to recognize in critically ill patients because of the marked coexisting inflammatory process. Lack of early recognition prevents timely resuscitation and effective antimicrobial therapy, resulting in increased morbidity and mortality. Measurement of a biomarker, such as C-reactive protein (CRP) concentration, in addition to history and physical signs, could facilitate diagnosis. Although frequently measured in clinical practice, few studies have reported on the pathophysiological role of this biomarker and its predictive value in critically ill patients. In this review, we discuss the pathophysiological role of CRP and its potential interpretation in the inflammatory processes observed in critically ill patients. |
