par Hiligsmann, Mickael;Kanis, John A;Compston, Juliet;Cooper, Cyrus;Flamion, Bruno ;Bergmann, Pierre ;Body, Jean-Jacques ;Boonen, Steven;Bruyere, Olivier;Devogelaer, Jean-Pierre;Goemaere, Stefan;Kaufman, Jean-Marc;Rozenberg, Serge ;Reginster, Jean-Yves
Référence Calcified tissue international, 93, 1, page (1-14)
Publication Publié, 2013-07
Référence Calcified tissue international, 93, 1, page (1-14)
Publication Publié, 2013-07
Article révisé par les pairs
Résumé : | We review the various aspects of health technology assessment in osteoporosis, including epidemiology and burden of disease, and assessment of the cost-effectiveness of recent advances in the treatment of osteoporosis and the prevention of fracture, in the context of the allocation of health-care resources by decision makers in osteoporosis. This article was prepared on the basis of a symposium held by the Belgian Bone Club and the discussions surrounding that meeting and is based on a review and critical appraisal of the literature. Epidemiological studies confirm the immense burden of osteoporotic fractures for patients and society, with lifetime risks of any fracture of the hip, spine, and forearm of around 40 % for women and 13 % for men. The economic impact is also large; for example, Europe's six largest countries spent |