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A new device for measurement of fibrin clot lysis: application to the euglobulin clot lysis time.

par Zouaoui Boudjeltia, Karim ;Cauchie, Philippe ;Remacle, Claude;Guillaume, Michel ;Brohée, Dany ;Hubert, J L;Vanhaeverbeek, Michel
Référence BMC biotechnology, 2, page (8)
Publication Publié, 2002-05

Article révisé par les pairs

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Résumé :

Determination of clot lysis times on whole blood, diluted whole blood, plasma or plasma fraction has been used for many years to assess the overall activity of the fibrinolytic system. We designed a completely computerised semi-automatic 8-channel device for measurement and determination of fibrin clot lysis. The lysis time is evaluated by a mathematical analysis of the lysis curve and the results are expressed in minute (range: 5 to 9999). We have used this new device for Euglobulin Clot Lysis Time (ECLT) determination, which is the most common test used in laboratories to estimate plasma fibrinolytic capacity.