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Anti-cyclic citrullinated peptide antibodies: a comparison of different assays for the diagnosis of rheumatoid arthritis.

par Debaugnies, France ;Servais, Geneviève;Badot, Valérie ;Noubouossié, Denis;Willems, Dominique ;Corazza, Francis
Référence Scandinavian journal of rheumatology, 42, 2, page (108-114)
Publication Publié, 2013

Article révisé par les pairs

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Résumé :

Anti-cyclic citrullinated peptide (anti-CCP) antibodies are highly specific markers of rheumatoid arthritis (RA). Considering the heterogeneity of the target antigens involved, and the test platforms and conjugates proposed in commercial anti-CCP assays, we assessed the diagnostic performances of four fully automated anti-CCP assays in a cohort of patients with RA compared to patients with other autoimmune and inflammatory disorders. We also evaluated the agreement between the qualitative results of these immunoassays.