Titre :
  • A phase I, dose-escalation study of the novel Polo-like kinase inhibitor volasertib (BI 6727) in patients with advanced solid tumours.
Auteur : Schöffski, Patrick ; Awada, Ahmad ; Dumez, Herlinde ; Gil, Thierry ; Bartholomeus, Sylvie ; Wolter, P ; Taton, Martine ; Fritsch, Holger ; Glomb, Patricia ; Munzert, Gerd
Informations sur la publication : European journal of cancer, 48, 2, (page 179-186)
Statut de publication : Publié, 2012-01
Sujet CREF : Cancérologie
Mots-clés : Dose escalation
Phase I
Polo-like kinase (Plk) inhibitor
Solid tumours
Volasertib (BI 6727)
Mots-clés MeSH : Adult
Aged
Antineoplastic Agents -- pharmacokinetics -- therapeutic use
Cohort Studies
Dose-Response Relationship, Drug
Female
Half-Life
Humans
Male
Middle Aged
Neoplasms -- drug therapy -- metabolism
Protein Kinase Inhibitors -- pharmacokinetics -- therapeutic use
Pteridines -- pharmacokinetics -- therapeutic use
Young Adult
Note : Clinical Trial, Phase I
Journal Article
Research Support, Non-U.S. Gov't
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:0959-8049 
info:doi/10.1016/j.ejca.2011.11.001
info:pii/S0959-8049(11)00874-4
info:pmid/22119200