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Current management of sepsis in critically ill adult patients.

par Vincent, Jean Louis ;Serrano, Elena Carrasco;Dimoula, Aikaterina
Référence Expert review of anti-infective therapy, 9, 7, page (847-856)
Publication Publié, 2011-07

Article révisé par les pairs

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Résumé :

Severe sepsis is a common occurrence in critically ill patients and a major cause of morbidity and mortality in this population. Management relies on the early identification and treatment of the underlying causative infection, adequate and rapid hemodynamic resuscitation, support of associated organ failure and modulation of the immune response with drotrecogin alfa (activated) when it is not contraindicated, and corticosteroids in severe septic shock. We will review current approaches to each of these categories.