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Utilization in vitro of [U-14C] glucose, [U-14C] fructose, L-[U-14C] alanine and [3H]-water in adipose-tissue fragments from Bar Harbor obese-hyperglycemic mice

par Christophe, Jean ;Dehaye, Jean-Paul ;Winand, Jacques
Référence Biochemical Society transactions, 2, 6, page (1214-1215)
Publication Publié, 1974

Article révisé par les pairs

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Résumé :

Decreased glucose uptake by the adipose tissue of obese hyperglycaemic mice, developing in the face of gross hyperinsulinism, was accompanied by increased lipogenesis de novo, and low α glycerophosphate synthesis from glycolysis and glyceroneogenesis. There was also some indication of a derangement of the flow of endogenous carbon utilizable for fatty acid synthesis.