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Effect of a low concentration of a cationic steroid antibiotic (CSA-13) on the formation of a biofilm by Pseudomonas aeruginosa.

par Nagant, Carole ;Feng, Y;Lucas, Bernard ;Braeckmans, K;Savage, Paul;Dehaye, Jean-Paul
Référence Journal of applied microbiology, 111, 3, page (763-772)
Publication Publié, 2011-09

Article révisé par les pairs

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Résumé :

Cationic steroids like CSA-13 have been designed by analogy with antimicrobial cationic peptides and have bactericidal properties. The purpose of this work was to evaluate the effect of a low concentration (1 mg l(-1)) of CSA-13 on the formation of a biofilm by eight strains of Pseudomonas aeruginosa (four mucoid and four nonmucoid strains) on an inert surface.