Titre :
  • Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo.
Auteur : Mustata, Roxana Camelia ; Van Loy, Tom ; Lefort, Anne ; Libert, Frédérick ; Strollo, Sandra ; Vassart, Gilbert ; Garcia, Marie-Isabelle
Informations sur la publication : EMBO reports, 12, 6, (page 558-564)
Statut de publication : Publié, 2011-06
Sujet CREF : Sciences biomédicales
Mots-clés : GPCR
intestinal crypts
LGR
stem cells
Mots-clés MeSH : Animals
Cell Differentiation
Gene Expression Profiling
Gene Expression Regulation, Developmental -- drug effects
Gene Knockout Techniques
Intestines -- cytology -- metabolism
Lithium Chloride -- pharmacology
Mice
Mice, Knockout
Organoids -- growth & development -- metabolism
Paneth Cells -- cytology
Phenotype
Receptors, G-Protein-Coupled -- genetics -- metabolism
Stem Cells -- cytology -- metabolism
Note : Journal Article
Research Support, Non-U.S. Gov't
FLWIN
SCOPUS: ar.j
Langue :
  • Anglais
Identificateurs : urn:issn:1469-221X 
info:doi/10.1038/embor.2011.52
info:pii/embor201152
info:pmid/21508962